In vitro drug interaction research have demonstrated that mitoxantrone did not inhibit CYP450 1A2, 2A6, 2C9, 2C19, 2D6, 2E1 and 3A4 across a wide concentration vary. The outcome of in vitro induction scientific tests are inconclusive, but propose that mitoxantrone may be a weak inducer of CYP450 2E1 action. Pharmacokinetic reports of your conversat
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Preclinical analysis of drug—drug interaction prospective: current standing of the application of primary human hepatocytes in the analysis of cytochrome P450 induction. Chem Biol Interact.Strategy for getting ready in vivo formulation：Take μL DMSO learn liquid, future increase μL PEG300， blend and clarify, subsequent insert μL Tween 80，